110V Sulzer/EE locomotive control systems utilise a battery made up of 48 cells to give a nominal battery open circuit potential difference of 110V, usually in the form of 12 x 4 cell battery units
74V EMD/GE?anything else utilise a battery made up of 32 cells to give a nominal battery open circuit potential difference of 74V, usually in the form of 8 x 4 cell battery units
What was done with NSU52 (based on HVTR C and X class DE's) was to replace the railway cranking batteries with N200 batteries, 8 x 6 cell battery units, still maintaining 48 cells for nominal 110V
On a 74V system that requires 32 cells, you would need 5 x 6 N120/150/200 batteries plus still require two more cells to make 32 cells. If you only used 5 x 6 cell batteries you will come up short on some voltage and cranking capacity, and when you have the engine running, the charging from the locomotive going into lesser number of cells wouldn't be good for the cells