More Metro Tunnel train pain is scheduled for next month when another suburban route is closed for weeks.

With major works ramping up again at South Yarra, buses will replace trains on the Sandringham line in Melbourne’s southeast between May 21 and June 9.

It comes amid construction of a new Town Hall station in the CBD, which has caused parts of Federation Square to be turned into a work site for piling ahead of excavation for tunnelling.

And the eastbound section of La Trobe St will be shut for a month between Swanston and Elizabeth streets from May 20 as the first stage of building an underground connection between Melbourne Central and a new State Library station.

Disgruntled Sandringham line commuters early in April. Picture: Lawrence PinderThe Melbourne Metro Tunnel will see 9km twin tunnels built under the city, connecting South Yarra to Kensington via five underground stations.

Premier Daniel Andrews said the government had no choice but to close rail lines and city streets to manage construction, but it would be managed with City of Melbourne.

“We’re going to have to ask Victorians for their patience and for them to make alternative arrangements to deal with the pace that we are doing,” he told reporters today.

“If we don’t have some construction related disruption now, we’ll have nothing but disruption and congestion into the future.”