Murrayville is a town on the section of the Mallee Highway between Ouyen and the South Australian border. It is about 24 kilometres (15 mi) east of the South Australian border and 536 kilometres (333 mi) north west of the state capital Melbourne, but 268 kilometres (167 mi) east of Adelaide. At the 2006 census, Murrayville had a population of 444.
The town's main industry is cereal crops, sheep and cattle, other industries are potato farming and other small crops. Irrigation is only supplied to the potato farms by an underground basin of high quality water. The only rail traffic seen at this location is bulk grains.